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- Chandrashekhar Patel
Faculty and Staff
Chandrashekhar Patel
| Title: | Associate Professor of Cell Biology & Anatomy Director of the Biomedical Studies Certificate Program |
| Department: | Cell Biology and Anatomy School of Medicine Columbia |
| Email: | Chandrashekhar.Patel@uscmed.sc.edu |
| Phone: | 803-216-3818 |
| Fax: | 803-216-3847 |
| Office: |
Cell Biology & Anatomy |
| Resources: | Lab Phone: 803-216-3829 |
Education
1979 Gujrat State University – Bachelors of Science – Microbiology
1981 University of Baroda – Masters of Science – Microbiology
1987 Indian Institute of Science – Ph.D. – Molecular Biology
Research
Molecular regulation of inflammation in vascular endothelial and smooth muscle cells
Publication
- Stress-induced phosphorylation of PACT reduces its interaction with TRBP and leads to PKR activation. Singh M, Castillo D, Patel CV, Patel RC. Biochemistry. 2011 May 31;50(21):4550-60. Epub 2011 May 6. PMID:21526770
- Essential role of PACT-mediated PKR activation in tunicamycin-induced apoptosis. Singh M, Fowlkes V, Handy I, Patel CV, Patel RC. J Mol Biol. 2009 Jan 16;385(2):457-68. Epub 2008 Nov 5.PMID:19007793
- Interaction of human tRNA-dihydrouridine synthase-2 with interferon-induced protein kinase PKR. Mittelstadt M, Frump A, Khuu T, Fowlkes V, Handy I, Patel CV, Patel RC. Nucleic Acids Res. 2008 Feb;36(3):998-1008. Epub 2007 Dec 20.PMID:18096616
- Differential regulation of HOXA9 expression by nuclear factor kappa B (NF-kappaB) and HOXA9. Trivedi CM, Patel RC, Patel CV. Gene. 2008 Jan 31;408(1-2):187-95. Epub 2007 Nov 13. PMID: 18068911
- Homeobox gene HOXA9 inhibits nuclear factor-kappa B dependent activation of endothelium.Trivedi CM, Patel RC, Patel CV. Atherosclerosis. 2007 Dec;195(2):e50-60. Epub 2007
Jun 27.
PMID: 17586512 - Regulation of vascular smooth muscle proliferation by heparin: inhibition of cyclin-dependent kinase 2 activity by p27(kip1). Fasciano S, Patel RC, Handy I, Patel CV. J Biol Chem. 2005 Apr 22;280(16):15682-9. Epub 2005 Feb 24.PMID:15731113
- Contribution of double-stranded RNA-activated protein kinase toward antiproliferative actions of heparin on vascular smooth muscle cells. Patel RC, Handy I, Patel CV. Arterioscler Thromb Vasc Biol. 2002 Sep 1;22(9):1439-44. PMID:12231563